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Spontaneous Long-term Persistent Elite HIV-control: The Right Model of Functional Cure

Ruiz-Mateos, Ezequiel

HIV elite controller (EC) is a heterogeneous phenotype. Some of these subjects show long-term persistent elite control with absence of viral blips, low levels of HIV reservoir, high HIV-specific T-cell response and low levels of inflammation compared to transient controllers, subjects that eventually lose spontaneous viral control ...


The threat of HIV Drug Resistance in low- and middle-income countries.

Poveda López, Eva

High rates of pre-treatment HIV drug resistance have been reported in low- and middle- income countries to first line therapy (i.e. NNRTIs) and other drugs that are always part of antiretroviral therapy combinations (i.e. lamivudine, emtricitabine). The current wave of transiting to dolutegravir as the new first-line therapy in these countries will be met with many challenges and will require engaging in a multi-sectoral approach, with the concerted effort of the scientific community, governments and the community ...


The Impact of Sex Hormones on HIV infection

Genescà, Meritxell

Female sex hormones, estradiol and progesterone, play a critical role mediating differences observed during all stages of HIV infection between males and females and thus, need to be considered in greater depth during basic and clinical research.


Lung cancer pain

Tuca, Albert

Lung cancer (PC) is the fourth most common neoplasm if both sexes are considered, after breast, prostate and colon cancer (incidence of 29.2 / 100,000). This neoplasm is the leading cause of cancer death among men and the second among women (overall mortality of 23 ...


Clinical case of Pain in Lung Cancer

Tuca, Albert

66-year-old patient with no known drug allergies and former smoker. Medical history: insulin-dependent diabetes mellitus, ischemic heart disease (acute myocardial infarction in 2005), spondylosis and disk protrusions in the lumbar spine and stage IIIA follicular lymphoma diagnosed in 2003, which was treated with polychemotherapy and is currently in complete remission ...