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    Spontaneous Long-term Persistent Elite HIV-control: The Right Model of Functional Cure

    Control espontáneo persistente de élite del VIH a largo plazo: el modelo correcto de cura funcional

    Authors: Ezequiel Ruiz-Mateos

    Keywords: HIV. Controller. Cure

    Abstract: HIV elite controller (EC) is a heterogeneous phenotype. Some of these subjects show long-term persistent elite control with absence of viral blips, low levels of HIV reservoir, high HIV-specific T-cell response and low levels of inflammation compared to transient controllers, subjects that eventually lose spontaneous viral control. This long-term spontaneous control for more than 30 years in some cases can be considered the right model of functional cure.


    Citation: Ezequiel Ruiz-Mateos. Control espontáneo persistente de élite del VIH a largo plazo: el modelo correcto de cura funcional. https://:doi.org/10.24175/sbd.2020.000012
    Received: June 18, 2020  Accepted: June 22, 2020  Published: October 23, 2020
    Copyright: © 2020 Ezequiel Ruiz-Mateos. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC), which allows, distribution, reproduction in any medium, provided the original author and source are credited and non-commercial use.
    Funding: I certify that no funding has been received for the conduct of this study and/or preparation of this manuscript.
    Conflicts of Interest: I have no conflicts of interest to declare

    

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About The Author/s
Ezequiel Ruiz-Mateos
eruizmateos-ibis@us.es
Clinic Unit of Infectious Diseases, Microbiology and Preventive Medicine; Institute of Biomedicine of Seville, IBiS, Virgen del Rocío University Hospital/CSIC/University of Seville, Seville, Spain


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DOI: 10.24175/sbd.2020.000012

Article with no peer review